diff --git a/dual_regression b/dual_regression new file mode 100755 index 0000000000000000000000000000000000000000..4806200f6b165d79075835bb4b16b5e7a56ca5ea --- /dev/null +++ b/dual_regression @@ -0,0 +1,128 @@ +#!/bin/sh + +# dual_regression - take group-ICA maps (etc) and get subject-specific versions of them (and associated timecourses) +# +# Stephen Smith and Christian Beckmann, FMRIB Image Analysis Group +# +# Copyright (C) 2011-2012 University of Oxford +# +# SHCOPYRIGHT + + +Usage() { + cat <<EOF + +dual_regression v0.5 (beta) + +***NOTE*** ORDER OF COMMAND-LINE ARGUMENTS IS DIFFERENT FROM PREVIOUS VERSION + +Usage: dual_regression <group_IC_maps> <des_norm> <design.mat> <design.con> <n_perm> <output_directory> <input1> <input2> <input3> ......... +e.g. dual_regression groupICA.gica/groupmelodic.ica/melodic_IC 1 design.mat design.con 500 grot \`cat groupICA.gica/.filelist\` + +<group_IC_maps_4D> 4D image containing spatial IC maps (melodic_IC) from the whole-group ICA analysis +<des_norm> 0 or 1 (1 is recommended). Whether to variance-normalise the timecourses used as the stage-2 regressors +<design.mat> Design matrix for final cross-subject modelling with randomise +<design.con> Design contrasts for final cross-subject modelling with randomise +<n_perm> Number of permutations for randomise; set to 1 for just raw tstat output, set to 0 to not run randomise at all. +<output_directory> This directory will be created to hold all output and logfiles +<input1> <input2> ... List all subjects' preprocessed, standard-space 4D datasets + +<design.mat> <design.con> can be replaced with just +-1 for group-mean (one-group t-test) modelling. +If you need to add other randomise option then just edit the line after "EDIT HERE" below + +EOF + exit 1 +} + +############################################################################ + +[ "$6" = "" ] && Usage + +ORIG_COMMAND=$* + +ICA_MAPS=`${FSLDIR}/bin/remove_ext $1` ; shift + +DES_NORM=--des_norm +if [ $1 = 0 ] ; then + DES_NORM="" +fi ; shift + +if [ $1 = "-1" ] ; then + DESIGN="-1" + shift +else + dm=$1 + dc=$2 + DESIGN="-d $1 -t $2" + shift 2 +fi + +NPERM=$1 ; shift + +OUTPUT=`${FSLDIR}/bin/remove_ext $1` ; shift + +while [ _$1 != _ ] ; do + INPUTS="$INPUTS `${FSLDIR}/bin/remove_ext $1`" + shift +done + +############################################################################ + +mkdir $OUTPUT +LOGDIR=${OUTPUT}/scripts+logs +mkdir $LOGDIR +echo $ORIG_COMMAND > $LOGDIR/command +if [ "$DESIGN" != -1 ] ; then + /bin/cp $dm $OUTPUT/design.mat + /bin/cp $dc $OUTPUT/design.con +fi + +echo "creating common mask" +j=0 +for i in $INPUTS ; do + echo "$FSLDIR/bin/fslmaths $i -Tstd -bin ${OUTPUT}/mask_`${FSLDIR}/bin/zeropad $j 5` -odt char" >> ${LOGDIR}/drA + j=`echo "$j 1 + p" | dc -` +done +ID_drA=`$FSLDIR/bin/fsl_sub -T 10 -N drA -l $LOGDIR -t ${LOGDIR}/drA` +cat <<EOF > ${LOGDIR}/drB +#!/bin/sh +\$FSLDIR/bin/fslmerge -t ${OUTPUT}/maskALL \`\$FSLDIR/bin/imglob ${OUTPUT}/mask_*\` +\$FSLDIR/bin/fslmaths $OUTPUT/maskALL -Tmin $OUTPUT/mask +\$FSLDIR/bin/imrm $OUTPUT/mask_* +EOF +chmod a+x ${LOGDIR}/drB +ID_drB=`$FSLDIR/bin/fsl_sub -j $ID_drA -T 5 -N drB -l $LOGDIR ${LOGDIR}/drB` + +echo "doing the dual regressions" +j=0 +for i in $INPUTS ; do + s=subject`${FSLDIR}/bin/zeropad $j 5` + echo "$FSLDIR/bin/fsl_glm -i $i -d $ICA_MAPS -o $OUTPUT/dr_stage1_${s}.txt --demean -m $OUTPUT/mask ; \ + $FSLDIR/bin/fsl_glm -i $i -d $OUTPUT/dr_stage1_${s}.txt -o $OUTPUT/dr_stage2_$s --out_z=$OUTPUT/dr_stage2_${s}_Z --demean -m $OUTPUT/mask $DES_NORM ; \ + $FSLDIR/bin/fslsplit $OUTPUT/dr_stage2_$s $OUTPUT/dr_stage2_${s}_ic" >> ${LOGDIR}/drC + j=`echo "$j 1 + p" | dc -` +done +ID_drC=`$FSLDIR/bin/fsl_sub -j $ID_drB -T 30 -N drC -l $LOGDIR -t ${LOGDIR}/drC` + +echo "sorting maps and running randomise" +j=0 +Nics=`$FSLDIR/bin/fslnvols $ICA_MAPS` +while [ $j -lt $Nics ] ; do + jj=`$FSLDIR/bin/zeropad $j 4` + + RAND="" + if [ $NPERM -eq 1 ] ; then + RAND="$FSLDIR/bin/randomise -i $OUTPUT/dr_stage2_ic$jj -o $OUTPUT/dr_stage3_ic$jj -m $OUTPUT/mask $DESIGN -n 1 -V -R" + fi + if [ $NPERM -gt 1 ] ; then + # EDIT HERE + RAND="$FSLDIR/bin/randomise -i $OUTPUT/dr_stage2_ic$jj -o $OUTPUT/dr_stage3_ic$jj -m $OUTPUT/mask $DESIGN -n $NPERM -T -V" + fi + + echo "$FSLDIR/bin/fslmerge -t $OUTPUT/dr_stage2_ic$jj \`\$FSLDIR/bin/imglob $OUTPUT/dr_stage2_subject*_ic${jj}.*\` ; \ + $FSLDIR/bin/imrm \`\$FSLDIR/bin/imglob $OUTPUT/dr_stage2_subject*_ic${jj}.*\` ; $RAND" >> ${LOGDIR}/drD + j=`echo "$j 1 + p" | dc -` +done +ID_drD=`$FSLDIR/bin/fsl_sub -j $ID_drC -T 60 -N drD -l $LOGDIR -t ${LOGDIR}/drD` +