diff --git a/requirements-extra.txt b/requirements-extra.txt
index fa62f9919dfc96bbca30c655db0cb1ae8308641c..dfa136dcb3b4989fcd39eb8ec3598aa2e8084dfc 100644
--- a/requirements-extra.txt
+++ b/requirements-extra.txt
@@ -1,4 +1,4 @@
 indexed_gzip>=0.7.0,<1
-wxpython>=3.0.2.0,<4.1
+wxpython==4.*
 trimesh>=2.22.28,<3
 rtree==0.8.3
diff --git a/requirements.txt b/requirements.txt
index ed88b9cbc855448445169c9f32d9c79722325403..9ccfa8c91c3a9b4d2e2867760be1acfedf65df57 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -1,5 +1,4 @@
 six==1.*
-deprecation>=1.*,<=2.*
 numpy==1.*
 scipy>=0.18
 nibabel>=2.2